Measurement uncertainty (MU) is defined as a parameter,
associated with the result of measurement that characterises the
dispersion of the values that could reasonably be attributed to the
measurand. By quantifying the possible spread of measurements an
estimate of the confidence in the result may be obtained.
MU stems from imprecision as a result of random effects on the
assay systems and so laboratories have to minimise the effects of
this and acknowledge this uncertainty.
Uncertainty within CDDFT
Within the examination process the laboratory can calculate the
measurement of uncertainty that is associated with a measured
analyte. We can use our internal and external quality performance
checks to assess the individual uncertainties within the
measurement system. For further information on our internal and
external quality control systems please contact the laboratory.
The MoU is the quantification of doubt, not error. The
co-efficient of variation (CV%) or standard deviation (SD) can be
considered as the combined uncertainty for results around the mean
of a particular concentration of quality control material.
For Haemoglobin, the Measurement Uncertainty in June 2017 (DMH)
= 2.29%. Therefore, a Haemoglobin reported as 100g/L would have a
Measurement Uncertainty of 97.7g/L - 102.3 g/L
Uncertainty of Mesurement (UoM) is calculated for all FBC
results for each QC lot number. The UoM is also calculated for
other Haematology results and Coagulation results. These
results are available on request from the Haematology Laboratory.
If you require this information please contact Haematology DMH
#43252 or Haematology UHND #32442.
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